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Peripheral Neuropathy

Surrogate Wnt agonists that phenocopy canonical Wnt and -catenin signalling

Additionally, manufacturers spend millions of dollars on research, development, clinical trials, and obtaining FDA approval

We previously demonstrated that growth attenuation of rv1127c in propionate is rescued by the addition of either vitamin B 12 or acetate (Basu et al, 2018), data that phenocopies Mtb mutants lacking MCC enzymes (Lee et al, 2013), thus supporting an unexpected role for Rv1127c in the MCC (Borah et al, 2021)

Nobody is on the hook if the batch is underdosed, cut with filler, or simply isnt the compound on the label